Von Willebrand disease is a disease that causes excessive bleeding due to a lack or reduced level of von Willebrand factor (vWF), a blood clotting protein. This disease is inherited as a dominant trait with incomplete penetrance, which means that not all dogs carrying the vWF mutation will show clinical signs of the disease.

Transmission

Incomplete dominance

Breed

Barbet, Bernese Mountain Dog, Brazilian Terrier, Cardigan Welsh Corgi, Coton de Tuléar, Dobermann, Dutch Partridge Dog, Dutch Shepherd, German Pinscher, Havanese, Irish Red and White Setter, Irish Setter, Labradoodle, Papillon, Pembroke Welsh Corgi, Phalène, Poodle, West Highland White Terrier