Dog

Leukocyte Adhesion Deficiency is an abnormality of the immune system. Due to the mutation, the leukocytes do not destroy bacteria and viruses leading to the death of affected puppies.

This cardiomyopathy leads to death without apparent cause at around 6-8 weeks of age in the Belgian Shepherd. Symptoms of this condition vary from individual to individual and include: vomiting, dyspnoea, enlarged heart, difficulty in locomotion, tremors.

Congenital myasthenic syndrome is caused by a malfunction in the transmission of nerve signals to the muscle, with symptoms usually appearing between 6 and 12 weeks of age. Affected puppies show generalised skeletal muscle weakness and fatigue, usually induced by exercise.

Cyclic neutropenia is a stem cell disease resulting in cyclic variation in the number of circulating neutrophils. The clinical signs of cyclic neutropenia are fever, diarrhoea, joint pain and respiratory, eye and skin infections. 

Centronuclear myopathy is a condition characterised by a generalised loss of tone, muscle control, exercise intolerance and clumsy gait. This myopathy usually manifests itself in puppies at the age of 2-5 months.

Scott syndrome is characterised by an increased tendency to bleed due to altered coagulation activity.

Copper toxicosis is characterised by an accumulation of copper in the liver and other organs leading to chronic hepatitis and cirrhosis of the liver which may progress to necrosis.

Cystinuria is a disorder that interferes with the proper reabsorption of cystine (an amino acid) in the kidneys leading to the formation of cystine crystals in the urine. Affected dogs have cystine crystals in the kidneys and/or bladder. 

Cystinuria is a disorder that interferes with the proper reabsorption of cystine (an amino acid) in the kidneys leading to the formation of cystine crystals in the urine. Affected dogs have cystine crystals in the kidneys and/or bladder. 

Cystinuria is a disorder that interferes with the proper reabsorption of cystine (an amino acid) in the kidneys leading to the formation of cystine crystals in the urine. Affected dogs have cystine crystals in the kidneys and/or bladder.