Horse

Fragile Foal Syndrome Type 1 (WFFS) is due to an abnormality in collagen synthesis characterised by hyperextensible, abnormally thin and fragile skin and mucous membranes that cause extensive lesions throughout the body. Signs of the disease are present from birth. Newborn foals are euthanised due to a poor prognosis for an incurable disease. The WFFS test is a patented test in Germany, France and the UK. For customers residing in these countries, please contact us.

Glycogen branching enzyme deficiency (GBED) is a disease affecting the storage of glycogen (sugar) in tissues. The disease is fatal because the brain, heart and muscles are unable to function properly. Affected animals may be stillborn, and foals that survive to term are usually euthanised.

Hereditary equine regional dermal asthenia is a genetic skin disease characterised by hyperextensible skin scars and severe lesions along the back of affected horses. Affected horses are usually euthanised.

Polysaccharide storage myopathy is a glycogen storage disease that accumulates in the muscle causing muscle damage. The symptoms of PSSM1 are muscle weakness, muscle atrophy, acute rhabdomyolysis and a reluctance of the horse to move. This test is patented and subcontracted to the patent holding laboratory.

Hyperkalaemic periodic paralysis (HYPP) is an inherited muscular disease causing muscle tremors and spasms that can be reminiscent of intermittent cramps and colic. Attacks may also be accompanied by respiratory noises resulting from paralysis of the upper airway muscles. This condition may result in sudden death of the animal.

Occipitoatlantoaxial malformation (OAAM) is a deformity of the first two vertebrae causing bone marrow compression and neurological damage. The mutation tested is associated with one of the forms of OAAM.

Junctional epidermolysis bullosa (JEB), also known as red foot disease, causes blistering of the skin epithelium and absence of skin on the lower limbs at birth. Affected foals are usually euthanised.

Malignant hyperthermia (MH) is characterised by muscle twitching, high temperature and irregular heartbeat. These symptoms can be triggered by halogenated anaesthetics, succinylcholine, stress or excitement.

Myostatin is a protein that regulates cell production in muscle. The MSTN mutation has been associated with race distance with C/C horses excelling over short distances and T/T horses over long distances.

This panel includes specific analyses related to agouti (HORSE-AG) and extension (HORSE-EXT) coat colour